Studies

CellWell record HH-334563

Blood-borne sphingosine 1-phosphate maintains vascular resistance, blood pressure, and cardiac function in mice

Ilaria Del Gaudio; Philippe Bonnin; Emilie Vessiéres; Estelle Robidel; Manuela C Garcia; Coralyne Proux; Alexandre Boutigny; Véronique Baudrie; Hoa T T Ha; Ludovic Couty; Sandrine Placier; Ivo Cornelissen; Nicolo Faedda; Nesrine Mebrek; Théo Morel; Anja Nitzsche; Tovo David; Stéphanie Baron; Olivia Lenoir; Pierre-Louis Tharaux; Maria-Christina Zennaro; Long N Nguyen; Timothy Hla; Daniel Henrion; Eric Camerer

2026

In plain language

In mice lacking all circulating sphingosine 1-phosphate, blood pressure was low and left ventricular systolic function reduced, supporting a role for albumin-bound S1P in maintaining blood pressure and cardiac function.

Evidence
Emerging
Design
Primary research (design unspecified)

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