CellWell record HH-329836
ADH5/ALDH2 Dehydrogenases and DNA Polymerase Theta Protect Hematopoietic Cells from Formaldehyde Challenge: Therapeutic Implications
Jessica Atkins; Anna-Mariya Kukuyan; M. Drzewiecka; T. Śliwiński; Monika M. Toma; Umeshkumar M Vekariya; Adam Karami; Tomasz Skorski
Blood · 2024
In plain language
DNA polymerase theta and ADH5/ALDH2 dehydrogenases provide complementary formaldehyde protection in hematopoietic cells; combined inhibition suppresses FLT3-ITD leukemia.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-329836
Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.
This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.