Studies

CellWell record HH-329034

Select intratumoral riboflavin-auxotrophic Enterococcus species enhance cell surface MR1 expression and MAIT TCR activation in lung cancer

Pakhi Birla; Lansaol Yang; Wanting Shan; Sakura Minamisawa; Omkar Dhaygude; Haritha Manoj; Alex J Lee; Jacqueline Ferri; Ying Zheng; Andrew Northcutt; Hongni Fan; Hadley Beauregard; Zhen Zeng; Kellie N Smith; Fyza Y Shaikh; Cynthia L Sears; Drew M Pardoll; Franck Housseau

2026

In plain language

Intratumoral Enterococcus species enhanced MAIT cell activation by upregulating MR1 expression on antigen-presenting cells in lung cancer.

Evidence
Emerging
Design
Primary research (design unspecified)

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