Studies

CellWell record HH-30206

Flame Retardant TDCIPP Reduces Heart Rate Variability Through Potential Direct Inhibition of Choline Acetyltransferase (ChAT) in Rats

Jiuhong Zhang; Chenyang Yue; Luling Nie; Wanqi Fu; Qingsong Xie; Zhuyi Jiang; Chao Wang; Jie Jiang; Yan Wu; Jianjun Liu; Xiao Chen

2026

In plain language

In young adult male rats given the flame retardant TDCIPP by mouth for 114 days, heart rate variability dropped by more than half, linked to reduced activity of an enzyme called ChAT that helps make the nerve signal acetylcholine.

Evidence
Emerging

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