CellWell record HH-300830
Quantitative Competition Binding of Fluorinated Ligands by Real-Time 19F In-Cell NMR to Assess Isoform Selectivity in Human Cells
Azzurra Costantino; Letizia Barbieri; Simone Giovannuzzi; Alessio Nocentini; Claudiu T Supuran; Enrico Luchinat
2026
In plain language
Real-time in-cell 19F NMR spectroscopy reliably quantified drug-target binding in living cells and ranked fluorinated benzenesulfonamide compounds by intracellular affinity.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-300830
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