Studies

CellWell record HH-288462

Targeted protein degradation dismantles undruggable targets to reverse immune evasion and therapy resistance in cancer

Furong Zhang; Qianheng Wang; Mingxuan Li; Tingting Wang; Ping Lei; Tao Huang; Zhenghao Wu

2026

In plain language

Targeted protein degradation reprograms tumor microenvironments from immunologically cold to hot states and demonstrates synergy with immune checkpoint blockade and adoptive cell therapy.

Evidence
Emerging
Design
Expert review

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