Studies

CellWell record HH-28179

Prenatal exposure to indoor VOCs impairs synaptic plasticity and cognitive function in mouse offspring via retinol metabolism disorder

Jing Sun; Xin Zhou; Changjian Xiao; Zhuoyan Li; Caifang Xu; Xiji Qin; Jieru Lu; Yurong Wu; Jinping Cheng; Sun Chen; Jianyuan Zhao; Kun Sun

2026

In plain language

In pregnant mice exposed to a formaldehyde-free paint VOC mixture throughout gestation, offspring later showed memory and spatial learning deficits, reduced brain synaptic proteins, and disrupted vitamin A metabolism genes, challenging the assumption that low-VOC building materials are fully safe.

Evidence
Emerging

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