Studies

CellWell record HH-263075

Environmental Contributions to Proton Sharing in Protein Low-Barrier Hydrogen Bonds

Jiusheng Lin; Oksana Gerlits; Daniel W Kneller; Kevin L Weiss; Leighton Coates; Jennifer L Clarke; Mark A Hix; Solomon Y Effah; Andrey Kovalevsky; Alice R Walker; Mark A Wilson; Mark A Wilson

2026

In plain language

Distal protein mutations can enhance proton delocalization in glutamate-aspartate hydrogen bonds by altering extended H-bonding networks and modulating proton transfer barriers.

Evidence
Emerging
Design
Primary research (design unspecified)

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