Studies

CellWell record HH-259383

METABOLITE MIMICRY REVEALS BUTYRATE ANALOG WITH SELECTIVE PROTECTIVE FUNCTIONS IN THE INTESTINAL MUCOSA

Ornelas, Alfredo; Countess, Jacob; Kim, Ji Yeon; Cohen, Rachel; Gomez, Brittany; Minhajuddin, Faiz; Sai, Kiranmayee Yenugudhati Vijaya; Zhou, Liheng; Dunn, Julia; Cartwright, Ian; Hall, Caroline; Bhagavatula, Geetha; Onyiah, Joseph; Roer, Rebecca; Dowdell, Alexander; Colgan, Sean

Oxford University Press ยท 2026

In plain language

The butyrate analog 3-chlorobutyrate enhanced epithelial barrier formation and was protective in colitis models, unlike butyrate itself.

Evidence
Emerging
Design
Primary research (design unspecified)

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