CellWell record HH-255318
Fluoride-Free Toothpastes for Caries Prevention: A Systematic Review of Clinical Evidence on Active Ingredients
Patrick Unterbrink; Erik Schulze Zur Wiesche; Bennett Tochukwu Amaechi; Joachim Enax
2026
In plain language
Hydroxyapatite and arginine toothpastes demonstrated clinically proven caries-preventive efficacy comparable to fluoride in randomized controlled trials.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-255318
Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.
This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.