Studies

CellWell record HH-2544

Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

Csanaky IL, et al.

Current Drug Metabolism ยท 2006

In plain language

This review explains how the liver pairs Phase II conjugation (sulfation, glucuronidation, glutathione binding) with specialized transport proteins that pump the finished, water-soluble metabolites out of liver cells for elimination.

Design
Systematic review

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