CellWell record HH-25302
Drinking water disinfection byproduct iodoacetic acid affects thyroid hormone synthesis in Nthy-ori 3-1 cells
Xiao J; Sha Y; Huang Y; Long K; Wu H; Mo Y; Yang Q; Dong S; Zeng Q; Wei X
Ecotoxicology and environmental safety · 2023
In plain language
In human thyroid follicular cells, the iodinated byproduct iodoacetic acid reduced expression of sodium iodide symporter, thyroid peroxidase and thyroglobulin, inhibited the cAMP/PKA pathway, and decreased iodine uptake.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-25302
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