Studies

CellWell record HH-240167

New sex hormone-binding globulin and estimated free testosterone reference intervals for children and adolescents: The effects of age, sex, BMI and oral contraceptives

Pierre Dürgen; Philip Johann Wölfle; Uta Ceglarek; Jürgen Kratzsch; Wieland Kiess; Mandy Vogel

2026

In plain language

In 3,109 German children and adolescents, sex hormone-binding globulin declined through childhood and plateaued after puberty, and lower levels were associated with higher BMI, most strongly in participants with overweight.

Evidence
Emerging
Design
Observational study

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