CellWell record HH-22299
Rapid shear stress-dependent ENaC membrane insertion is mediated by the endothelial glycocalyx and the mineralocorticoid receptor
Cosgun ZC; Sternak M; Fels B; Bar A; Kwiatkowski G; Pacia MZ; Herrnböck L; Lindemann M; Stegbauer J; Höges S; Chlopicki S; Kusche-Vihrog K
Cellular and molecular life sciences : CMLS · 2022
In plain language
In endothelial cells, the epithelial sodium channel together with the glycocalyx acted as a shear stress sensor mediating vasodilation, and in pathophysiological conditions that mechanotransduction was lost.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-22299
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