Studies

CellWell record HH-21853

Magnolol attenuates depressive-like behaviors by polarizing microglia towards the M2 phenotype through the regulation of Nrf2/HO-1/NLRP3 signaling pathway

Tao W; Hu Y; Chen Z; Dai Y; Hu Y; Qi M

Phytomedicine : international journal of phytotherapy and phytopharmacology ยท 2021

In plain language

In mice, magnolol relieved depressive-like behaviours, suppressed pro-inflammatory cytokines and promoted M2 microglial markers, upregulating Nrf2 and HO-1 expression.

Evidence
Emerging
Design
Animal study

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