CellWell record HH-212000
Systemic Mastocytosis, KIT and the Effects of KIT Tyrosine Kinase Inhibitors on Mast Cell and Basophil Activation ...
Valent, Peter; Hartmann, Karin; Stefanzl, Gabriele; Filik, Yüksel; Bauer, Karin; Degenfeld-Schonburg, Lina; Gleixner, Karoline V.; Siebenhaar, Frank; Niedoszytko, Marek B.; Sperr, Wolfgang Reinhard; Aghaallaei, Narges; Hoermann, Gregor; Sabato, Vito; Orfao, Alberto; Arock, Michel; Akin, Cem
DataCite · 2026
In plain language
Systemic mastocytosis is characterized by uncontrolled mast cell expansion in tissues, typically involving KIT D816V mutation, causing mediator symptoms and potentially life-threatening anaphylaxis.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-212000
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