Studies

CellWell record HH-211613

Hepcidin as a Molecular Hub of Iron Homeostasis: From BMP -- SMAD Signaling to Therapeutic Modulation

Andrea Duminuco; Alessandro Costa; Federica Pilo; Salvatore Scarso; Cesarina Giallongo; Sebastiano Giallongo; Annalisa Santisi; Arianna Sbriglione; Laura Santocono; Giovanni Caocci; Giuseppe A. Palumbo

MDPI Open Access Publishing ยท 2026

In plain language

Hepcidin dysregulation underlies multiple disorders: insufficient hepcidin drives hemochromatosis and iron overload, while elevated hepcidin contributes to anemia of inflammation and chronic kidney disease.

Evidence
Emerging
Design
Primary research (design unspecified)

Read it on DOI

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