CellWell record HH-2105
Cortisol metabolism and visceral obesity: role of 11beta-hydroxysteroid dehydrogenase type I enzyme and reduced co-factor NADPH
Agarwal AK
Molecular and Cellular Endocrinology ยท 2004
In plain language
This mechanistic paper proposes that altered cofactor availability for the 11beta-HSD1 enzyme in fat tissue may drive excess local cortisol regeneration seen in visceral obesity.
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-2105
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