Studies

CellWell record HH-20279

Glymphatic Dysfunction in bipolar disorder: A scoping review and integrative pathophysiological framework

Zhangyan Shan; Qianyu Zhu; Shuai Wang; Yu Xia; Yuanyuan Yang; Lin Tian

2026

In plain language

A scoping review finds preliminary neuroimaging evidence that glymphatic markers are altered in bipolar disorder and correlate with illness duration, and that lithium may act partly by modulating choroid plexus circadian rhythm and aquaporin-4.

Evidence
Emerging
Design
Expert review

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-20279

Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.