CellWell record HH-20189
A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction
Gunduz-Cinar O; Castillo LI; Xia M; Van Leer E; Brockway ET; Pollack GA; Yasmin F; Bukalo O; Limoges A; Oreizi-Esfahani S; Kondev V; Báldi R; Dong A; Harvey-White J; Cinar R; Kunos G; Li Y; Zweifel LS; Patel S; Holmes A
Neuron · 2023
In plain language
In mice, endocannabinoid activity at CB1 receptors in prefrontal cortex-to-amygdala synapses tracked and supported fear extinction learning, shown using optogenetics and endocannabinoid biosensor imaging.
- Evidence
- Emerging
- Design
- Animal study
Cite this record: https://thecellwell.org/studies/HH-20189
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