CellWell record HH-20180
Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood-brain barrier alterations
Dudek KA; Paton SEJ; Binder LB; Collignon A; Dion-Albert L; Cadoret A; Lebel M; Lavoie O; Bouchard J; Kaufmann FN; Clavet-Fournier V; Manca C; Guzmán M; Campbell M; Turecki G; Mechawar N; Flamand N; Lavoie-Cardinal F; Silvestri C; Di Marzo V; Menard C
Nature neuroscience · 2025
In plain language
In male mice, astrocytic CB1 expression in the nucleus accumbens dampened stress-induced anxiety and depression-like behaviors; loss was observed in depressed humans.
- Evidence
- Emerging
- Design
- Animal study
Cite this record: https://thecellwell.org/studies/HH-20180
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