CellWell record HH-20051
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
Marrs WR; Blankman JL; Horne EA; Thomazeau A; Lin YH; Coy J; Bodor AL; Muccioli GG; Hu SS; Woodruff G; Fung S; Lafourcade M; Alexander JP; Long JZ; Li W; Xu C; Möller T; Mackie K; Manzoni OJ; Cravatt BF; Stella N
Nature neuroscience · 2010
In plain language
In cells and brain tissue, ABHD6 controls 2-arachidonoylglycerol accumulation and efficacy at cannabinoid receptors by postsynaptic degradation of the endocannabinoid.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-20051
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