Studies

CellWell record HH-19978

Protective Effects of Monoacylglycerol Lipase Inhibition in Rats with Severe Acute Pancreatitis and Its Possible Mechanism

Tong Su; Hongwei Xu; Ruixia Wang; Tong Xiao; Jing Wang; Shulei Zhao

2026

In plain language

In rats with severe acute pancreatitis, the MAGL inhibitor JZL184 lowered serum amylase, ALT, and creatinine levels and reduced lung and pancreatic tissue damage, altering NO/cGMP/phosphodiesterase signaling.

Evidence
Emerging
Design
Animal study

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