Studies

CellWell record HH-19467

Functional neuroimaging of fatty acid amide hydrolase inhibition in posttraumatic stress disorder: a randomized clinical trial

Tansey R; Perini I; Petrie GN; Haggarty CJ; Mazurka R; Yngve A; Mina S; Jones MR; Engelbrektsson H; Capusan AJ; Hill MN; Heilig M; Mayo LM

Translational psychiatry ยท 2026

In plain language

In a randomized trial of 100 adults with post-traumatic stress disorder, four weeks of FAAH inhibition raised anandamide but produced no difference in brain functional connectivity or emotional task activation versus placebo.

Evidence
Established
Design
Randomized controlled trial
Studied in
Human

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