CellWell record HH-19465
Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice
Deol P; Ruegger P; Logan GD; Shawki A; Li J; Mitchell JD; Yu J; Piamthai V; Radi SH; Hasnain S; Borkowski K; Newman JW; McCole DF; Nair MG; Hsiao A; Borneman J; Sladek FM
Gut microbes ยท 2023
In plain language
A high linoleic acid soybean oil diet lowered protective endocannabinoid compounds in the mouse intestine, shifted gut microbial composition and raised colitis susceptibility, linking dietary fat quality to intestinal endocannabinoid signalling.
- Evidence
- Emerging
- Design
- Animal study
- Studied in
- Human, Animal
Cite this record: https://thecellwell.org/studies/HH-19465
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