CellWell record HH-19463
Anti-inflammatory ω-3 endocannabinoid epoxides
McDougle DR; Watson JE; Abdeen AA; Adili R; Caputo MP; Krapf JE; Johnson RW; Kilian KA; Holinstat M; Das A
Proceedings of the National Academy of Sciences of the United States of America · 2017
In plain language
Cytochrome P450 epoxygenases convert the omega-3 endocannabinoids made from DHA and EPA into epoxide metabolites that lowered IL-6 and raised IL-10 in cells, partly through CB2 receptor activation.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
- Studied in
- Human, Animal
Cite this record: https://thecellwell.org/studies/HH-19463
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