CellWell record HH-19462
n-3 polyunsaturated N-acylethanolamines are CB2 cannabinoid receptor-preferring endocannabinoids
Alharthi N; Christensen P; Hourani W; Ortori C; Barrett DA; Bennett AJ; Chapman V; Alexander SPH
Biochimica et biophysica acta. Molecular and cell biology of lipids ยท 2018
In plain language
In receptor assays, omega-3 derived N-acylethanolamines activated CB2 but not CB1 receptors, while palmitoylethanolamide, stearoylethanolamide and oleoylethanolamide activated neither, indicating these abundant lipids are not true endocannabinoids.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
- Studied in
- Human, Animal
Cite this record: https://thecellwell.org/studies/HH-19462
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