Studies

CellWell record HH-19391

Upregulated NLRP3 inflammasome activation is attenuated by anthocyanins in patients with nonalcoholic fatty liver disease: A case-control and an intervention study

Zhu X; Lin X; Zhang P; Liu Y; Ling W; Guo H

Clinics and research in hepatology and gastroenterology ยท 2022

In plain language

In NAFLD patients, a 12-week randomized trial found 320 mg/day anthocyanins was associated with markedly reduced NLRP3 inflammasome activity, lowering the inflammatory signals IL-1 beta and IL-18 that are elevated in fatty liver.

Evidence
Established
Design
Randomized controlled trial
Studied in
Human

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