CellWell record HH-19351
Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program
Edwards MG; Anderson RM; Yuan M; Kendziorski CM; Weindruch R; Prolla TA
BMC genomics ยท 2007
In plain language
In mouse skeletal muscle, 712 genes differed between young and old animals and caloric restriction reversed 87% of these changes; the aging pattern pointed to activation of a p53-mediated transcriptional program.
- Evidence
- Emerging
- Design
- Animal study
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-19351
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