CellWell record HH-19251
Folate rescues lithium-, homocysteine- and Wnt3A-induced vertebrate cardiac anomalies
Han M; Serrano MC; Lastra-Vicente R; Brinez P; Acharya G; Huhta JC; Chen H; Linask KK
Disease Models & Mechanisms ยท 2009
In plain language
Lithium and homocysteine each disrupted mouse embryonic heart development by potentiating Wnt-beta-catenin signalling, and folate supplementation reversed the disruption from either exposure.
- Evidence
- Emerging
- Design
- Animal study
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-19251
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