CellWell record HH-19243
Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride
Agrawal S; Gollapudi S; Gupta S; Agrawal A
Experimental Gerontology ยท 2013
In plain language
Lithium chloride lowered TNF-alpha and IL-6 release from dendritic cells of older adults and reduced interferon-gamma secretion by primed T cells, but did not raise IL-10 as it did in younger cells.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
- Studied in
- Human
Cite this record: https://thecellwell.org/studies/HH-19243
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