Studies

CellWell record HH-192173

Halogens as Thyroid Disruptors: Molecular Modeling of Competitive Interference with Iodine in Thyroid Hormone Biosynthesis

Luís Jesuíno de Oliveira Andrade; Gabriela Correia Matos de Oliveira; Alcina Maria Vinhaes Bittencourt; Osmário Jorge de Mattos Salles

2026

In plain language

Fluoride, chloride, bromide, and perchlorate computationally showed stronger binding to thyroid peroxidase and sodium-iodide symporter than iodide, supporting halogen disruption of thyroid synthesis.

Evidence
Emerging
Design
Preprint

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