CellWell record HH-19145
Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells.
Shao L; Young LT; Wang JF
Biological psychiatry ยท 2005
In plain language
In cultured rat brain cortex cells, chronic exposure to lithium and valproate blocked the glutamate-triggered rise in calcium, oxidative damage and cell death, without changing these measures under normal, non-stimulated conditions.
- Studied in
- Animal, Cell / in vitro
Cite this record: https://thecellwell.org/studies/HH-19145
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