Studies

CellWell record HH-19140

A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells.

Kurgan N; Whitley KC; Maddalena LA; Moradi F; Stoikos J; Hamstra SI

Cells ยท 2019

In plain language

In cultured mouse muscle cells, lithium chloride at concentrations matching blood levels used for bipolar disorder reduced GSK3 enzyme activity by 86 percent and increased markers of muscle cell fusion and differentiation.

Studied in
Human, Animal, Cell / in vitro

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