CellWell record HH-19139
Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice.
Clément-Lacroix P; Ai M; Morvan F; Roman-Roman S; Vayssière B; Belleville C
Proceedings of the National Academy of Sciences of the United States of America · 2005
In plain language
In three strains of mice, including ones lacking a Wnt receptor and ones prone to osteoporosis, oral lithium chloride for four weeks increased bone mass and activated Wnt signaling genes in bone forming cells.
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-19139
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