CellWell record HH-19138
Low dose lithium supplementation activates Wnt/β-catenin signalling and increases bone OPG/RANKL ratio in mice.
Kurgan N; Bott KN; Helmeczi WE; Roy BD; Brindle ID; Klentrou P
Biochemical and biophysical research communications · 2019
In plain language
In mice given low-dose lithium for six weeks, bone tissue showed activated Wnt signaling and a higher ratio of bone-protecting OPG to RANKL protein, changes associated with increased bone formation.
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-19138
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