CellWell record HH-19137
Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner.
Bosche B; Molcanyi M; Rej S; Doeppner TR; Obermann M; Müller DJ
Frontiers in physiology · 2016
In plain language
In lab experiments using mouse, pig and human blood vessel tissue, lithium at concentrations similar to blood levels used clinically for bipolar disorder improved vessel relaxation responses and reduced vessel lining leakiness by lowering a signaling protein called MLC phosphorylation.
Cite this record: https://thecellwell.org/studies/HH-19137
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