CellWell record HH-19136
Atherosclerosis induced by a high-fat diet is alleviated by lithium chloride via reduction of VCAM expression in ApoE-deficient mice.
Choi SE; Jang HJ; Kang Y; Jung JG; Han SJ; Kim HJ
Vascular pharmacology ยท 2010
In plain language
In ApoE-deficient mice fed a high-fat diet, lithium chloride lowered blood glucose and reduced both artery plaque buildup and a vessel wall inflammation marker called VCAM-1, an effect tied to blocking the enzyme GSK-3 beta.
- Studied in
- Human, Animal, Cell / in vitro
Cite this record: https://thecellwell.org/studies/HH-19136
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