Studies

CellWell record HH-170770

Homocysteine-induced endothelial dysfunction through mediating endoplasmic reticulum stress

Xiaoxue Zhang; Shengtao Xiong; Liang Long; Yue Xuan; Hongjing You; Yue Xu; Minyi Zhang

2026

In plain language

In mice and endothelial cells, homocysteine increased adhesion molecule expression and reduced tight junction protein in brain tissue, and these effects were linked to endoplasmic reticulum stress involving glucose-regulated protein 78.

Evidence
Emerging
Design
Primary research (design unspecified)

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