Studies

CellWell record HH-168885

Nighttime-restricted feeding disrupts spermatogenesis in mice via gut microbiota-derived KYNA homeostasis

Donghui Yang; Dong Xie; Chuan Li; Yan Liu; Xiangyu Cheng; Junfeng Liu; Qizhong Lu; Lanlan Jia; Wentao Liu; Qihui Luo; Zhengli Chen; Chao Huang

2026

In plain language

Nighttime-restricted feeding in mice reduced sperm quality and testicular function through elevated gut-derived kynurenic acid, a mechanism not observed with daytime restricted feeding.

Evidence
Emerging
Design
Primary research (design unspecified)

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