Studies

CellWell record HH-163838

Divergent impacts of estradiol/testosterone reduction on biological aging: optimal HRT window in females recommended

Yicheng Ma; Junming Han; Qihang Li; Xiao Jiang; Yuan Li; Keke Zhang; Ling Gao

2026

In plain language

In UK Biobank data, estradiol decline linked to 0.18 -- 0.29 years biological age acceleration in females; HRT initiated at ages 56 -- 60 produced maximal sustained biological age reduction.

Evidence
Emerging
Design
Primary research (design unspecified)

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