CellWell record HH-163340
Mouse offspring conceived by in vitro fertilization exhibit accelerated reproductive aging through premature ovarian insufficiency
Eric A Rhon-Calderon; Cassidy N Hemphill; Alexandra J Savage; Ana Domingo-Muelas; Zhengfeng Liu; Christopher J Krapp; Laren Riesche; Nicolas Plachta; Richard M Schultz; Marisa S Bartolomei
2026
In plain language
In vitro fertilization accelerated reproductive aging in female offspring by inducing premature ovarian insufficiency with reduced follicle reserve and epigenetic changes consistent with reproductive decline.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-163340
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