Studies

CellWell record HH-158879

Effects of Zinc Supplementation on Glycemic Control, Insulin Resistance, Inflammation and Oxidative Stress in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Jessica Paola Loaiza-Giraldo; Florencia Amigo-Fierro; Camila Ignacia Cancino-Castro; Matias Donoso-Emig; Murtaja Satea; Ignacia Farías-Quinteros; Alejandro Bruna-Mejias; Pablo Nova-Baeza; Mathias Orellana-Donoso; Héctor Gutiérrez-Espinoza; Gloria Cifuentes-Suazo; Juan Sanchis-Gimeno; Maria Piagkou; Vitor E Valenti; Jose E Leon-Rojas; Juan José Valenzuela-Fuenzalida

2026

In plain language

A meta-analysis of 18 randomized trials (1,023 participants) found zinc supplementation increased plasma zinc levels and was associated with reduced insulin resistance, lower CRP and malondialdehyde, and higher antioxidant capacity in people with diabetes or prediabetes.

Evidence
Established
Design
Meta-analysis

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