Studies

CellWell record HH-158099

Oral Immunotherapy-Induced Changes in IgE, IgG, and IgA: A Review of Antibody Isotype Shifts and Their Clinical Relevance in Food Allergy

Giovanni Lasagni; Laura Vetrugno; Chiara Maria Maggiore; Chiara Galassetti; Giulia Di Colo; Francesco Pavan; Andrea Costantino; Lorenzo Dagna

2026

In plain language

Oral immunotherapy induces transient elevation of allergen-specific IgE early, followed by sustained increases in IgG4 and IgA, with these antibody changes correlating with desensitization and proposed tolerance mechanisms.

Evidence
Emerging
Design
Expert review

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