Studies

CellWell record HH-152946

Calorie-restricted oat diet is associated with zonulin and short-chain fatty acid response in metabolic syndrome: a randomized controlled trial

Linda Klümpen; Aakash Mantri; Anna Donkers; Waldemar Seel; Birgit Stoffel-Wagner; Martin Coenen; Matthias Schmid; Leonie Weinhold; Fabian Grein; Patrick Newels; Janis Bedarf; Ullrich Wüllner; Peter Stehle; Marie-Christine Simon

2026

In plain language

A 2-day calorie-restricted diet high in oats lowered serum zonulin and raised plasma butyric acid compared to controls in adults with metabolic syndrome, while a 6-week isocaloric oat diet showed no change.

Evidence
Established
Design
Randomized controlled trial

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