Studies

CellWell record HH-148372

Optimal serum potassium concentrations in heart failure: an individual patient data meta-analysis

Ryohei Ono; Misato Chimura; Kieran F Docherty; Alasdair D Henderson; Ross Campbell; Akshay S Desai; Michel Komajda; Milton Packer; Marc A Pfeffer; Bertram Pitt; John R Teerlink; Faiez Zannad; Muthiah Vaduganathan; Orly Vardeny; Mingming Yang; Pardeep S Jhund; Scott D Solomon; John J V McMurray

2026

In plain language

A pooled analysis of over 46,000 heart failure patients found the lowest mortality risk at baseline serum potassium of 4.2 to 5.0 mmol/L, with hypokalemia strongly linked to worse outcomes in HFrEF.

Evidence
Established
Design
Meta-analysis

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-148372

Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.