CellWell record HH-14776
Primary cilia in the hypothalamic AgRP neurons mediate metabolic effects of butyrate.
Rijal S; Yang DJ; Doan KV; Lyoo SH; Lee A; Choi YH; Shin DM; Kim KW
Nature communications ยท 2026
In plain language
In mice, butyrate activated primary cilia on hypothalamic AgRP neurons through increased histone acetylation, a mechanism found essential for its appetite-suppressing and glucose-regulating effects on the brain's feeding center.
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-14776
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