CellWell record HH-14191
EGCG Regulates the Effect of HDAC6 on Oxidative Stress of Human Periodontal Ligament Fibroblasts Induced by Lipopolysaccharide.
Jie Y; Xia L; ZeHui P; YuanZhu L; Bin C; Yaohua L; Si G; GuoHui B; JianGuo L; Qin F
Immunity, inflammation and disease ยท 2025
In plain language
In LPS-stimulated human periodontal ligament fibroblasts, EGCG reduced TNF-alpha and IL-1beta, activated the Nrf2 pathway, and inhibited HDAC6 expression, mechanisms linked to reduced oxidative stress and inflammation.
- Studied in
- Human, Cell / in vitro
Cite this record: https://thecellwell.org/studies/HH-14191
Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.
This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.