Studies

CellWell record HH-13866

Anticancer Effects of Broccoli Sprout Extract and Sulforaphane Through ROS-Induced MAPK Pathway in Breast Cancer Cells and Xenografts.

Lee SO; Yu JE; Subedi L; Phuyal S; Bamjan AD; Yoon G; Joo SH; Oh SJ; Park JW; Shim JH

Antioxidants (Basel, Switzerland) ยท 2026

In plain language

In breast cancer cell lines and rat xenograft models, broccoli sprout extract and its compound sulforaphane triggered ROS-driven MAPK signaling, mitochondrial dysfunction, and apoptosis, reducing cell viability and inhibiting tumor growth.

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