Studies

CellWell record HH-13799

Hyaluronic acid-butyrate conjugates for barrier restoration in atopic dermatitis: CD44-mediated retention and inflammation-responsive release.

Liu T; Chen G; Zhao C; Fu J; Xie A; Cai B; Zhang L; Lv H

Carbohydrate polymers ยท 2026

In plain language

In a mouse model, hyaluronic acid-butyrate conjugates targeted inflamed, CD44-overexpressing skin to release butyrate locally, accelerating lesion healing, restoring barrier proteins, and reducing inflammatory cytokines in atopic-dermatitis-like skin.

Studied in
Animal

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